frailty

Digging deeper: factors that modify and/or mediate sensory-cognitive associations in the CLSA

Cognitive decline (which is a normal part of aging) and dementia (which is an...

Frailty in older adults with multiple sclerosis (MS): investigating associations with psychological health and lifestyle factors

The intersection of multiple sclerosis (MS) and aging presents unique challenges as it combines...

Frailty in survivors of cancer – exploring rehabilitation to improve frailty outcomes (REHAB-FIC)

Although both frailty and cancer can occur at any age, they are predominantly seen...

Using metabolomics to examine the association between diet, inflammation, and frailty in the Canadian Longitudinal Study on Aging (CLSA)

Frailty is a condition where our bodies become less resilient and struggle to cope...

Health deficit accumulation in relation to cardiovascular disease burden

Frailty in cardiovascular disease is a problem related to poor quality of life, hospital...

Biological dysregulation as a mechanism of unhealthy aging in older adults

Evidence suggests that a breakdown of the numerous biological systems that maintain good health...

Identification of genetic variants associated with frailty – a genome-wide association study

The world population is getting older, and we are observing the same phenomenon in...

Broad and deep longitudinal analysis in neurodegenerative disease (BRAIN): Identifying and predicting trajectories of decline in cognitive and physical function using data from CLSA linked to routinely collected health system data (follow-up)

Declines in various aspects of cognition such as memory, language skills and reasoning are...

Examining frailty in Canada from a population health perspective

Project Findings Frailty is a medical condition of reduced function and health in older...

Individual, social, and environmental determinants of physical activity: a machine learning and temporal network approach

Physical inactivity is associated with a higher risk of disability, disease, and mortality, especially...

A comprehensive approach to quantifying chronic inflammation in older adults

Identification of metabolic perturbations driving frailty in aging