genetics

Genetic analyses of healthy aging: buffering and exploratory analyses

Genetic variants are like spelling differences in genes. Genetic buffering is when a variant...

Identification of genetic variants associated with frailty – a genome-wide association study

The world population is getting older, and we are observing the same phenomenon in...

Adverse childhood experiences, genomic influences, and acceleration of biological aging in middle-aged and older adults in the CLSA

Adverse childhood experiences (ACEs), including childhood exposure to abuse, neglect, and intimate partner violence...

Predicting clinical manifestations of Parkinson’s Disease using polygenic risk scores

People living with Parkinson’s disease experience a variety of symptoms including problems with movement,...

Bitter taste receptors and COVID-19

Proteins that help taste sensation (bitter taste receptors or T2Rs) have recently been shown...

An investigation into the genetic basis of human intrinsic capacity

The World Health Organization (WHO) has reframed the definition of healthy aging as the...

Genetic analyses of mental health trajectories in aging adults

As people age, changes in mental health can occur. The genetic and environmental factors...

Investigating the interplay between genetics, social, and environmental factors in nutrition, aging, and health in the CLSA

Cognitive aging in middle and older-aged Canadians: consideration of genetic risk, modifiable factors, and biological sex

Understanding the genetic and environmental determinants of metabolism- and aging-related phenotypes

Canadian Longitudinal Study on Aging (CLSA): building a COVID-19 platform for research in Canada

Gene by psychosocial determinants (G*E) of lifelong wellness and foundational work for longitudinal geo-referenced multilevel analysis bridging MoNNET and CLSA data into The Montreal Synthetic Ecosystem