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genome-wide association studies (GWAS)

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Degenerative protein modifications (DPMs) as molecular mediators connecting socio-demographic profile to the onset of age-related diseases

We have identified a set of degenerative protein modifications (DPMs) in patients’ tissues, resulting...

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Identification of genetic variants associated with frailty – a genome-wide association study

The world population is getting older, and we are observing the same phenomenon in...

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Interactive visualization of genetic variant-trait associations in the CLSA dataset

The CLSA study collected data on thousands of traits and hundreds of millions of...

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Identifying novel genetic factors predisposing to inherited cardiac disorders

Inherited cardiac disorders arise from genetic variations and can manifest as cardiomyopathies or arrhythmic...

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Identification and statistical analysis for risk factors for vision loss and bone loss by joint analysis of genetic, imaging and biomedical data

Vision loss and bone loss are two major disorders in older adults because of...

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Identifying genetic risk variants and developing a deep learning prediction model for disability development in the elderly: a study using the Canadian Longitudinal Study on Aging

Disability in the elderly is a significant health issue with a growing impact on...

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Prediction of short stature and its consequences

Children with idiopathic short stature (ISS) are defined by height below 2 standard deviations...

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Genetic analyses of mental health trajectories in aging adults

As people age, changes in mental health can occur. The genetic and environmental factors...

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Sex-specific environmental and genetic determinants of COPD in middle-aged and older Canadian adults: an analysis of CLSA data

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Genetic determinants of neurological diseases and their risk factors

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Genetic determinants of cardiometabolic disease and its risk factors

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The genetics and epidemiology of aortic stenosis and coronary artery disease in the Canadian population

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