Year:
Applicant:
Trainee:
Institution:
Email:
macdonmj@mcmaster.ca
Keywords:
carotid artery distensibility
carotid intima-media thickness (c-IMT)
functional health
glucose metabolism
inflammation
lipid metabolism
mobility
vascular health
Project ID:
190246
Approved Project Status:
Project Summary
Canadians are living longer and it is crucial to understand and identify modifiable risk factors associated with aging for early disease detection. Carotid artery wall thickness (cIMT) and stiffness measure blood vessel health and serve as early indicators of Cardiovascular disease (CVD) risk with aging. Aging is also associated with functional limitations. There have been no population-based studies examining the relationship between vascular and functional health in aging adults. Our project will leverage collected cIMT ultrasound images to provide a comprehensive analysis of vascular health (cIMT and stiffness). Associations between vascular and functional health and the influence of inflammatory and metabolic biomarkers will be assessed.
