Year:
Applicant:
Institution:
Email:
daniel.taliun@mcgill.ca
Keywords:
complex diseases
genetics
genome-wide association studies (GWAS)
monogenic diseases
omics
polygenic risk scores
rare genetic variants
Project ID:
2109005
Approved Project Status:
Project Summary
Our research aims to identify genomic factors affecting complex traits and diseases and use these discoveries to improve disease risk prediction and drug targets identification and validation. Using data from large population-based biobanks (e.g. CLSA, CARTaGENE, UK Biobank), we will assess patterns of rare and common genetic variations across different ancestries, evaluate their effects on disease risk, and elucidate mechanisms by which they act.