Using metabolomics to examine the association between diet, inflammation, and frailty in the Canadian Longitudinal Study on Aging (CLSA)
Frailty is a condition where our bodies become less resilient and struggle to cope…
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January 22, 2025
Approved Projects
Find out how the CLSA research platform is being used.
Health deficit accumulation in relation to cardiovascular disease burden
Frailty in cardiovascular disease is a problem related to poor quality of life, hospital…
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Parkinson’s disease risk and phenoconversion: a polygenic risk score approach
Parkinson’s disease (PD) is a common neurodegenerative disease in older adults. Health conditions like…
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Read the latest peer-reviewed scientific publications.
Identification of Metabolic Characteristic–Pancreatic Ductal Adenocarcinoma Associations Using Mendelian Randomization and Metabolomics
Xiang Y, Zhang C, Wang J, Cheng Y, Wang K, Wang L, Tong Y, Yan D. Identification of Metabolic Characteristic-Pancreatic Ductal Adenocarcinoma Associations Using Mendelian Randomization and Metabolomics. 2025 Jan 20;56. doi.org/10.1007/s12029-025-01173-4
Assessing the causal effect of genetically predicted metabolites and metabolic pathways on vitiligo: Evidence from Mendelian randomization and animal experiments
Li G, Qu B, Zheng T, Cheng Y, Li P, Liu Z, Zhao J. Assessing the causal effect of genetically predicted metabolites and metabolic pathways on vitiligo: Evidence from Mendelian randomization and animal experiments. J Steroid Biochem Mol Biol. 2025 Mar;247:106677. doi: 10.1016/j.jsbmb.2025.106677. Epub 2025 Jan 14. PMID: 39818343.
A nested case-control study evaluating the relationship between adverse childhood experiences and immune-mediated inflammatory disease in the Canadian Longitudinal Study on Aging
O’Mahony J, Bernstein CN, Marrie RA. A nested case-control study evaluating the relationship between adverse childhood experiences and immune-mediated inflammatory disease in the Canadian Longitudinal Study on Aging. BMJ Open. 2025 Jan 20;15(1):e087133. doi: 10.1136/bmjopen-2024-087133. PMID: 39833007; PMCID: PMC11749297.
Frailty and gynecologic cancer: A cross-sectional analysis of the Canadian Longitudinal Study on Aging
Lavecchia M, Marucci M, Raina P, Jimenez W, Nguyen JMV. Frailty and gynecologic cancer: a cross-sectional analysis of the Canadian Longitudinal Study on Aging. International Journal of Gynecological Cancer. 2025 Jan 17;101642. doi.org/10.1016/j.ijgc.2025.101642
Researcher Resources
Data collection, data access and data support documentation for researchers.
Researcher FAQs
Find answers to some of the most common queries about the CLSA.
Participant Resources
To ensure you are fully informed, this section provides links to information packages, consent forms and other documents relevant to your participation.
Participant FAQs
Find answers to some of the most common queries about the CLSA.
Webinar Recordings
All CLSA webinars are recorded and available on the CLSA website and CLSA YouTube channel.
